Dvl3 Antikörper

Antigen: Dvl3

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN411474

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit polyclonal antibody. Detects Dvl3 from Human/mouse/rat samples. Tested in Western blotting. Other applications have not been determined.

Gen-ID: 13544

Immunogen: Synthetic peptide surrounding amino acid 583 of mouse Dvl3

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Dvl1, Dvl2, and Dvl3 are mammalian homologs of Dsh (disheveled) proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins, Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). The optimal concentrations should be determined individually. A ~80 kDa band and a smaller ~45 kDa cleavage fragment can be detected.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Beschränkungen: Nur für Forschungszwecke einsetzbar