Dickkopf Homolog 4 (Xenopus Laevis) (DKK4) Antikörper

Antigen: Dickkopf Homolog 4 (Xenopus Laevis) (DKK4)

Synonyme: DKK-4, MGC129562, MGC129563

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN411467

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-DKK4 polyclonal antibody. Reacts with human/mouse/rat. Detects ~40 Kda band in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3894BP-50) is also available.

Weitere Bezeichnung: DKK4

Gen-ID: 234130

Immunogen: Synthetic peptide surrounding amino acid 179 of mouse Dkk4

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Xenopus Dickkopf (Dkk) was initially discovered as a Wnt antagonist that plays an important role in head formation. By far, four members of Dkk have been identified in mammals. Each Dkk molecule contains two conserved cysteine-rich domains which are separated by a 50-55 amino acid linker region. Dkk4 is a secreted glycoprotein and has three immune-reactive sites at 15-17kDa, 30-32kDa and at 40kDa.

Spezifität: The antibody detects ~40 kDa of Dkk4 in samples from human, mouse and rat origins. Reactivity to other species has not been determined.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~40 kDa of Dkk4 in samples from human, mouse and rat origins. Reactivity to other species has not been determined.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-Dkk4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Forschungsgebiet: Stammzellen, Wnt

Beschränkungen: Nur für Forschungszwecke einsetzbar