Decorin (DCN) Antikörper

Antigen: Decorin (DCN)

Synonyme: CSCD, PG40, PGII, PGS2, DSPG2, SLRR1B, MGC94682, DCN, MGC127810

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Schwein

Applikation: Western Blot (WB)

Produktnummer: ABIN411461

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-Decorin polyclonal antibody. Detects 22 kDa Decorin fragment. Reacts with human/mouse/rat/pig/rabbit. Tested in Western blot. Other spplications have not been determined.

Weitere Bezeichnung: Decorin

Gen-ID: 1634

Immunogen: Synthetic peptide surrounding amino acid 130 of human Decorin

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-β. It is believed that decorin also plays a role in the cell cycle of chondrocytes.

Spezifität: The antibody detects ~22 kDa protein representing the Decorin fragment generated by digestion of human Decorin by MMP-3.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects ~22 kDa protein representing the Decorin fragment generated by digestion of human Decorin by MMP-3.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit anti-Decorin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 25% glycerol, 0.5% BSA, and 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Forschungsgebiet: Stammzellen, Extrazelluläre Matrix

Beschränkungen: Nur für Forschungszwecke einsetzbar