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CAMP Responsive Element Binding Protein 1 (CREB1) Antikörper

Antigen

CAMP Responsive Element Binding Protein 1 (CREB1)

Synonyme CREB, MGC9284, Creb, Creb-1, AV083133, 2310001E10Rik, 3526402H21Rik, JAL, hJAL, ATCE1, CREB3, CREB4, AIBZIP, CREB1, creb1, MGC52669, creb, MGC69285, MGC55598, zgc:55598, Creb1, DKFZp468J2311
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen

Reaktivität
Alternativen

Human, Maus, Ratte (Rattus)

Applikation
Alternativen Western Blot (WB), Immunpräzipitation (IP), Immunhistochemie (IHC)
Produktnummer ABIN411455
Menge 100 µg  (0.5 mg/ml)
Preis 258,88 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung

Produktmerkmale 100 ug Rabbit Polyclonal Antibody. Reacts with human/mouse/rat. Detect 43 kDa CREB and also 28-36 kDa CREB isoforms in Western blot analysis. Blocking peptide (Cat.# 3360RBP-50) is available separately.
Weitere Bezeichnung CREB
Gen-ID 81646
Immunogen Synthetic peptide surrounding amino acid 109 of rat CREB
Isotyp IgG  (Passende Sekundärantikörper)
Beschreibung Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Spezifität The antibody recognizes 43 kDa CREB from samples of human, mouse and rat origins.

Anwendungen

Applikationshinweise Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 43 kDa CREB from samples of human, mouse and rat origins.
Konzentration 0.5 mg/ml
Reinigung Affinity Purified Antibody
Buffer 100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Lagerung Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "CAMP Responsive Element Binding Protein 1 (CREB1)", Typ "Antikörper" finden
Wirte Kaninchen (147), Maus (28)
Reaktivitäten Human (167), Maus (127), Ratte (Rattus) (124), Rind (Kuh) (41), Hund (37), Schwein (36), Huhn (35), Schaf (34), Affe (2), Xenopus laevis (2), Kaninchen (1), Zebrafisch (Danio rerio) (1)
Applikationen Western Blot (WB) (114), Immunfluoreszenz (IF) (50), Immunhistochemie (IHC) (50), Immunhistochemie (Paraffinschnitte) (IHC (p)) (45), Durchflusszytometrie (FACS) (38), Enzyme Immunoassay (EIA) (23), Immunpräzipitation (IP) (20), ELISA (19), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (4), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Dot Blot (Dot) (2), ELISA (Detektionsantikörper) (2), Immunoelectron Microscopy (IEM) (2), Elektromobilitäts-Experimente (EMSA) (1)
Konjugate Biotin (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitope pSer133 (28), pSer129 (10), pS133 (4), pSer142 (4), pSer121 (3), N-Term (1), p43 (1)