BRK Antikörper

Antigen: BRK

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN411443

Produktbeschreibung

Produktmerkmale: 100 ug affinity purified rabbit anti-Brk polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blotting. Blocking peptide (Cat.# 3847BP-50) is also available.

Gen-ID: 5753

Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 508 of human Brk

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Breast tumor kinase, Brk (also known as PTK6), is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation.

Anwendungen

Applikationshinweise: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~57 kDa Brk of human, mouse, and rat origins. Reactivity to other species has not been tested.

Konzentration: 0.5 mg/ml

Reinigung: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit anti-Brk polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Lagerung: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Forschungsgebiet: Krebs, Tyrosinkinasen

Beschränkungen: Nur für Forschungszwecke einsetzbar