ACTR1A Antikörper (Middle Region)

Produktnummer ABIN406684

Produktdetails anti-ACTR1A Antikörper

Target: ACTR1A (Alpha Centractin (ACTR1A))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACTR1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AIKERACYLS INPQKDETLE TEKAQYYLPD GSTIEIGPSR FRAPELLFRP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ACTR1A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACTR1A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 376 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ACTR1A

Target: ACTR1A (Alpha Centractin (ACTR1A))

Andere Bezeichnung: ACTR1A (ACTR1A Produkte)

Synonyme: ARP1 antikoerper, CTRN1 antikoerper, Arp1 antikoerper, alpha-Arp1 antikoerper, arp1 antikoerper, centractin antikoerper, ctrn1 antikoerper, ACTR1A antikoerper, ARP1 actin related protein 1 homolog A antikoerper, ARP1 actin-related protein 1A, centractin alpha antikoerper, ARP1 actin-related protein 1 homolog A, centractin alpha antikoerper, ARP1 actin related protein 1 homolog A L homeolog antikoerper, alpha-centractin antikoerper, actin-2 antikoerper, ACTR1A antikoerper, Actr1a antikoerper, actr1a.L antikoerper, actr1a antikoerper, PTRG_02540 antikoerper, PAAG_06972 antikoerper, MCYG_01044 antikoerper, VDBG_00685 antikoerper, MGYG_00946 antikoerper, DICPUDRAFT_88548 antikoerper, PGTG_04034 antikoerper, Tsp_06409 antikoerper

Hintergrund: ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARP1, CTRN1
Protein Interaction Partner: HUWE1, SUMO2, UBC, NUP133, DCTN4, MYCBP, DCTN3, DCTN2, ACTR1B, LMNB1, COG3, ACTR10, SMURF1, RRS1, PSMD1, PSMC4, MYH9, MCM7, COPS5, CUL1, CUL3, SUMO1, Cep76, Actr1a, Dctn1, Capza1, HDAC6, SPTBN2, SPTBN1, NUMA1, BICD2,
Protein Size: 376

Molekulargewicht: 41 kDa

Gen-ID: 10121

NCBI Accession: NM_005736, NP_005727

UniProt: P61163

Pathways: M Phase