MPP7 Antikörper (N-Term)

Produktnummer ABIN406339

Produktdetails anti-MPP7 Antikörper

Target: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MPP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPALSTGSGS DTGLYELLAA LPAQLQPHVD SQEDLTFLWD MFGEKSLHSL

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MPP7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MPP7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 576 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MPP7 Antikörper (ABIN406339)

Stucke, Timmerman, Vandekerckhove, Gevaert, Hall: "The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation." in: Molecular biology of the cell, Vol. 18, Issue 5, pp. 1744-55, (2007) (PubMed).

Details zu MPP7

Target: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Andere Bezeichnung: MPP7 (MPP7 Produkte)

Synonyme: 1110068J02Rik antikoerper, 2810038M04Rik antikoerper, 5430426E14Rik antikoerper, AI415104 antikoerper, Gm955 antikoerper, dlg3 antikoerper, hmp antikoerper, membrane palmitoylated protein 7 antikoerper, membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) antikoerper, membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) antikoerper, MPP7 antikoerper, Mpp7 antikoerper, mpp7a antikoerper

Hintergrund: MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).[supplied by OMIM].
Alias Symbols: FLJ32798, RP11-218D6.5
Protein Interaction Partner: AMOT, Wwtr1, Yap1, UBC,
Protein Size: 576

Molekulargewicht: 65 kDa

Gen-ID: 143098

NCBI Accession: NM_173496, NP_775767

UniProt: Q5T2T1

Pathways: Cell-Cell Junction Organization