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KREMEN1 Antikörper (N-Term)

KREMEN1 Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Hund, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN405712
  • Target Alle KREMEN1 Antikörper anzeigen
    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
    Bindungsspezifität
    • 16
    • 12
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 43
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Hund, Pferd
    Wirt
    • 40
    • 3
    • 2
    Kaninchen
    Klonalität
    • 41
    • 4
    Polyklonal
    Konjugat
    • 21
    • 5
    • 5
    • 5
    • 5
    • 4
    Dieser KREMEN1 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 34
    • 20
    • 13
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    WKYCEIPACQ MPGNLGCYKD HGNPPPLTGT SKTSNKLTIQ TCISFCRSQR
    Homologie
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KREMEN1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human KREMEN1
    Top Product
    Discover our top product KREMEN1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 475 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
    Andere Bezeichnung
    KREMEN1 (KREMEN1 Produkte)
    Synonyme
    KREMEN1 antikoerper, krm1 antikoerper, kremen antikoerper, kremem1 antikoerper, KREMEN antikoerper, KRM1 antikoerper, AV002070 antikoerper, Kremen antikoerper, Krm1 antikoerper, si:ct737139.1 antikoerper, si:dkeyp-7c9.1 antikoerper, kringle containing transmembrane protein 1 antikoerper, kringle containing transmembrane protein 1 S homeolog antikoerper, KREMEN1 antikoerper, kremen1 antikoerper, Kremen1 antikoerper, kremen1.S antikoerper
    Hintergrund
    KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
    Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1
    Protein Interaction Partner: DKK1,
    Protein Size: 475
    Molekulargewicht
    50 kDa
    Gen-ID
    83999
    NCBI Accession
    NM_001039570, NP_001034659
    UniProt
    Q96MU8
    Pathways
    WNT Signalweg
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