MARCH1 Antikörper (N-Term)

Produktnummer ABIN405536

Produktdetails anti-MARCH1 Antikörper

Target: MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LQASSPTTGT APRSQSRLSV CPSTQDICRI CHCEGDEESP LITPCRCTGT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MARCH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 272 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MARCH1

Target: MARCH1 (Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))

Andere Bezeichnung: MARCH1 (MARCH1 Produkte)

Synonyme: MARCH-I antikoerper, RNF171 antikoerper, 2900024D24Rik antikoerper, BB085186 antikoerper, RGD1305148 antikoerper, MARCH1 antikoerper, DKFZp459K1250 antikoerper, membrane associated ring-CH-type finger 1 antikoerper, membrane-associated ring finger (C3HC4) 1 antikoerper, MARCH1 antikoerper, March1 antikoerper

Hintergrund: MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alias Symbols: DKFZp564M1682, FLJ20668, MARCH-I, RNF171
Protein Interaction Partner: TNFRSF10A, UBE2H, UBE2D1, CDC34, TFRC, UBC, HLA-DRB1, HLA-DRA, PPP2R1B, PPP2R1A, CD86,
Protein Size: 272

Molekulargewicht: 31 kDa

Gen-ID: 55016

NCBI Accession: NM_017923, NP_060393