EXOSC2 Antikörper (Middle Region)

Produktnummer ABIN405355

Produktdetails anti-EXOSC2 Antikörper

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOSC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AEVQAVFSDG AVSLHTRSLK YGKLGQGVLV QVSPSLVKRQ KTHFHDLPCG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOSC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EXOSC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 293 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EXOSC2 Antikörper (ABIN405355)

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Details zu EXOSC2

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Andere Bezeichnung: EXOSC2 (EXOSC2 Produkte)

Synonyme: EXOSC2 antikoerper, exosc2 antikoerper, MGC97533 antikoerper, RRP4 antikoerper, Rrp4p antikoerper, hRrp4p antikoerper, p7 antikoerper, Rrp4 antikoerper, fa97b01 antikoerper, wu:fa97b01 antikoerper, zgc:110117 antikoerper, exosome component 2 antikoerper, exosome component 2 L homeolog antikoerper, EXOSC2 antikoerper, exosc2 antikoerper, Bm1_33895 antikoerper, PTRG_00114 antikoerper, Exosc2 antikoerper, exosc2.L antikoerper

Hintergrund: EXOSC2 belongs to the exosome, a RNA-processing complex, which is at least involved in the 3' processing of the 7S pre-rRNA to the mature 5.8S rRNA. It exhibits a 3'-5' exoribonuclease activity.
Alias Symbols: RRP4, Rrp4p, hRrp4p, p7
Protein Interaction Partner: GPX1, ST6GALNAC1, MRPL48, EXOSC7, RNF8, GALNT13, ZNF408, AICDA, METTL22, UBC, UPF1, MDC1, BARD1, EXOSC5, EXOSC4, EXOSC3, DEK, RAN, EXOSC9, DIS3L, DIS3, UBD, CAND1, HDGF, MEPCE, SKIV2L2, EXOSC6, KHSRP, MPP6, EXOSC8, UPF3A, UPF2,
Protein Size: 293

Molekulargewicht: 32 kDa

Gen-ID: 23404

NCBI Accession: NM_014285, NP_055100

UniProt: Q13868

Pathways: SARS-CoV-2 Protein Interaktom