MNDA Antikörper (C-Term)
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- Target Alle MNDA Antikörper anzeigen
- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MNDA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KCEKGDKLRL FCLQLRTVDR KLKLVCGSHS FIKVIKAKKN KEGPMNVN
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MNDA. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human MNDA
- Top Product
- Discover our top product MNDA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 407 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
- Andere Bezeichnung
- MNDA (MNDA Produkte)
- Synonyme
- PYHIN3 antikoerper, A730048F03 antikoerper, Ifi205b antikoerper, myeloid cell nuclear differentiation antigen antikoerper, interferon activated gene 211 antikoerper, MNDA antikoerper, Ifi211 antikoerper
- Hintergrund
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The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage.MNDA may act as a transcriptional activator/repressor in the myeloid lineage. It plays a role in the granulocyte/monocyte cell-specific response to interferon. MNDA stimulates the DNA binding of the transcriptional repressor protein YY1.The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PYHIN3
Protein Interaction Partner: PRMT6, WHSC1L1, PRMT7, TP53, RBL2, RB1, HOXB2, CDK2, CDK1,
Protein Size: 407 - Molekulargewicht
- 46 kDa
- Gen-ID
- 4332
- NCBI Accession
- NM_002432, NP_002423
- UniProt
- P41218
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