Kv2.1/KCNB1 Antikörper (Middle Region)

Produktnummer ABIN404910

Produktdetails anti-Kv2.1/KCNB1 Antikörper

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kv2.1/KCNB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YIDADTDDEG QLLYSVDSSP PKSLPGSTSP KFSTGTRSEK NHFESSPLPT

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KCNB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 858 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Kv2.1/KCNB1

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Andere Bezeichnung: KCNB1 (KCNB1 Produkte)

Synonyme: KCNB1 antikoerper, Kcnb1 antikoerper, Kcr1-1 antikoerper, Kv2.1 antikoerper, Shab antikoerper, DRK1PC antikoerper, DRK1 antikoerper, KV2.1 antikoerper, h-DRK1 antikoerper, potassium voltage-gated channel subfamily B member 1 antikoerper, potassium voltage-gated channel, Shab-related subfamily, member 1 antikoerper, potassium channel, voltage gated Shab related subfamily B, member 1 antikoerper, potassium voltage gated channel, Shab-related subfamily, member 1 antikoerper, KCNB1 antikoerper, kcnb1 antikoerper, LOC100541632 antikoerper, Kcnb1 antikoerper

Hintergrund: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DRK1, KV2.1, h-DRK1
Protein Interaction Partner: STX1A, KCNG3, KCNG4, KCNV1, KCNB2, KCNG1, KCNB1, SRC, SUMO1, NEDD4L, KCNV2, KCNG2, KCNS3, PTPRE, SNAP25, KCNH1,
Protein Size: 858

Molekulargewicht: 96 kDa

Gen-ID: 3745

NCBI Accession: NM_004975, NP_004966

UniProt: Q14721

Pathways: Synaptic Membrane