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PARP16 Antikörper (Middle Region)

PARP16 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Kaninchen, Rind (Kuh), Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN404894
  • Target Alle PARP16 Antikörper anzeigen
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 36
    • 20
    • 20
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Kaninchen, Rind (Kuh), Hund
    Wirt
    • 35
    • 1
    Kaninchen
    Klonalität
    • 36
    Polyklonal
    Konjugat
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PARP16 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 15
    • 13
    • 13
    • 13
    • 5
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    PKYFVVTNNQ LLRVKYLLVY SQKPPKSRAS SQLSWFSSHW FTVMISLYLL
    Homologie
    Cow: 79%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 80%, Rabbit: 86%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PARP16. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human PARP16
    Top Product
    Discover our top product PARP16 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 323 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Di Paola, Micaroni, Di Tullio, Buccione, Di Girolamo: "PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1." in: PLoS ONE, Vol. 7, Issue 6, pp. e37352, (2012) (PubMed).

  • Target
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Andere Bezeichnung
    PARP16 (PARP16 Produkte)
    Synonyme
    PARP16 antikoerper, zgc:77744 antikoerper, ARTD15 antikoerper, C15orf30 antikoerper, pART15 antikoerper, BC055447 antikoerper, C79952 antikoerper, PARP-16 antikoerper, LRRGT00109 antikoerper, RGD1306243 antikoerper, poly(ADP-ribose) polymerase family member 16 antikoerper, poly(ADP-ribose) polymerase family member 16 L homeolog antikoerper, poly (ADP-ribose) polymerase family, member 16 antikoerper, PARP16 antikoerper, parp16.L antikoerper, parp16 antikoerper, Parp16 antikoerper
    Hintergrund
    Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
    Alias Symbols: C15orf30, FLJ20509, FLJ25281, pART15
    Protein Interaction Partner: GMCL1, UBC, NEDD4,
    Protein Size: 323
    Molekulargewicht
    36 kDa
    Gen-ID
    54956
    NCBI Accession
    NM_017851, NP_060321
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