Claudin 18 Antikörper (Middle Region)

Produktnummer ABIN404887

Produktdetails anti-Claudin 18 Antikörper

Target: Claudin 18 (CLDN18)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YHASGHSVAY KPGGFKASTG FGSNTKNKKI YDGGARTEDE VQSYPSKHDY

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CLDN18. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CLDN18

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 261 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Claudin 18

Target: Claudin 18 (CLDN18)

Andere Bezeichnung: CLDN18 (CLDN18 Produkte)

Synonyme: claudin-18 antikoerper, CLDN18 antikoerper, SFTA5 antikoerper, SFTPJ antikoerper, claudin 18 L homeolog antikoerper, claudin 18 antikoerper, cldn18.L antikoerper, CLDN18 antikoerper, Cldn18 antikoerper

Hintergrund: CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells (Niimi et al., 2001 [PubMed 11585919]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-282 AY358479.1 28-309 283-1864 AK098474.1 274-1855 1865-2307 BM785703.1 143-585 2308-2868 AK098474.1 2297-2857 2869-3359 AY102073.1 394-884
Alias Symbols: SFTA5, SFTPJ
Protein Size: 261

Molekulargewicht: 28 kDa

Gen-ID: 51208

NCBI Accession: NM_016369, NP_057453

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C