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TCF7L1 Antikörper (N-Term)

TCF7L1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN404738
  • Target Alle TCF7L1 Antikörper anzeigen
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    Bindungsspezifität
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 35
    • 17
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen
    Wirt
    • 33
    • 1
    • 1
    Kaninchen
    Klonalität
    • 34
    • 1
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser TCF7L1 Antikörper ist unkonjugiert
    Applikation
    • 19
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    NDELIPFQDE GGEEQEPSSD SASAQRDLDE VKSSLVNESE NQSSSSDSEA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TCF7L1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1
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    Discover our top product TCF7L1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 588 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TCF7L1 (Transcription Factor 7-Like 1 (T-Cell Specific, HMG-Box) (TCF7L1))
    Andere Bezeichnung
    TCF7L1 (TCF7L1 Produkte)
    Synonyme
    TCF-3 antikoerper, TCF3 antikoerper, Tcf-3 antikoerper, Tcf3 antikoerper, bHLHb21 antikoerper, tcf3c antikoerper, tcf3d antikoerper, xtcf3 antikoerper, XTCF-3 antikoerper, tcf7l1 antikoerper, tcf3b antikoerper, TCF-3-A antikoerper, tcf-3 antikoerper, tcf3 antikoerper, tcf3a antikoerper, zTcf-3 antikoerper, transcription factor 7 like 1 antikoerper, transcription factor 7 like 1 (T cell specific, HMG box) antikoerper, transcription factor 7 like 1 L homeolog antikoerper, transcription factor 7 like 1 S homeolog antikoerper, transcription factor 7 like 1b antikoerper, transcription factor 7 like 1a antikoerper, TCF7L1 antikoerper, Tcf7l1 antikoerper, tcf7l1.L antikoerper, tcf7l1.S antikoerper, tcf7l1b antikoerper, tcf7l1a antikoerper
    Hintergrund
    TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
    Alias Symbols: TCF-3, TCF3
    Protein Interaction Partner: UBC, mdfic, Mdfi, DAZAP2, CTNNB1,
    Protein Size: 588
    Molekulargewicht
    63 kDa
    Gen-ID
    83439
    NCBI Accession
    NM_031283, NP_112573
    UniProt
    Q9HCS4
    Pathways
    WNT Signalweg, Stem Cell Maintenance
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