POGZ Antikörper (N-Term)

Produktnummer ABIN401435

Der Kaninchen Polyklonal anti-POGZ Antikörper wird verwendet zum Nachweis von POGZ in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Huhn, Makake, Anubis-Paviane und Schimpanse. Er wurde validiert für WB und EIA.

Kurzübersicht für POGZ Antikörper (N-Term) (ABIN401435)

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Huhn, Makake, Anubis-Paviane, Schimpanse

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POGZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-POGZ Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody is known to react with Pogz protein.

Kreuzreaktivität (Details): Species reactivity (expected):Human, Canine, Cattle, Rat, Chimpanzee, Macaque, Olive Baboon, Chicken, Short-tailed opossum.
Species reactivity (tested):Mouse.

Aufreinigung: Affinity chromatography

Immunogen: Synthetic peptide corresponding to a region near the N-terminus of mouse Pogz protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/150,000. Western Blot: 1/3,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.564 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu POGZ

Target: POGZ (Pogo Transposable Element with ZNF Domain (POGZ))

Andere Bezeichnung: POGZ

Hintergrund: Pogz is a zinc-finger protein containing at least 8 C2H2 zinc fingers, a CENP-B (centromere protein-B) domain, and a DDE domain found in the bacterial transposase/retroviral integrase family. Members of this family of integrases share structural homologies and show similar catalytic activity to the RAG1 and RAG2 proteins that initiate V(D)J recombination in lymphoid progenitors. Mouse Pogz has a human homolog with a base pair similarity of 90 % and amino acid similarity of 93 % for the full length protein. In humans at least 3 variants have been predicted and they are all similar at the N-terminus. A number of expressed sequence tags (ESTAs) cloned from murine undifferentiated ES cells and Lin-/c-Kit+/Sca-1+ hematopoietic stem cell cDNA libraries correspond to the Pogz gene, further underlining an important function for this gene in stem cells. In mice, deletion of the gene in all tissues early in embryogenesis has been shown to be lethal.Synonyms: KIAA0461, Pogo transposable element with ZNF domain, SUHW5, Suppressor of hairy wing homolog 5, ZNF280E, ZNF635

Gen-ID: 229584

NCBI Accession: NP_766271

UniProt: Q8BZH4