ABCB5 Antikörper (Internal Region)

Produktnummer ABIN401433

Produktdetails anti-ABCB5 Antikörper

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Bindungsspezifität: Internal Region

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCB5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific for ABCB5 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Monkey (85 %), Rat (68 %), Mouse (62 %).
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography

Immunogen: Synthetic peptide corresponding to residues corresponding to an internal region of Human ABCB5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10,000-1/50,000. Western Blot: 1/20,000. Trial Size: ELISA: 1/10,000- 1/15,000. Western Blot: 1/10,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu ABCB5

Target: ABCB5 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 5 (ABCB5))

Andere Bezeichnung: ABCB5 (ABCB5 Produkte)

Synonyme: ABCB5alpha antikoerper, ABCB5beta antikoerper, EST422562 antikoerper, 9230106F14Rik antikoerper, RGD1566342 antikoerper, ABCB5 antikoerper, mdr1 antikoerper, im:7158730 antikoerper, wu:fc18f02 antikoerper, wu:fi81f06 antikoerper, ATP binding cassette subfamily B member 5 antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 5 antikoerper, ATP-binding cassette sub-family B member 5 antikoerper, ABCB5 antikoerper, Abcb5 antikoerper, abcb5 antikoerper, TGME49_249820 antikoerper, PAAG_04387 antikoerper, VDBG_00160 antikoerper, VDBG_02292 antikoerper

Hintergrund: ATP-Binding Cassette proteins comprise a superfamily of transporters with a wide variety of substrates. ABCB5 is a novel member of the human P-glycoprotein family. It functions as a determinant of membrane potential and regulator of cell fusion in physiologic skin progenitor cells. Cell fusion is thought to contribute to tissue differentiation. ABCB5 is predominantly expressed in melanoma cells and is a novel molecular marker for a distinct subset of chemoresistant stem cell phenotype-expressing tumor cells among human epidermal melanocytes. It has been identified as a novel drug transporter in human malignant melanoma. ABCB5 is a rhodamine efflux transporter. This antibody product is intended to be used to confirm cellular localization and expression level of ABCB5.Synonyms: ATP-binding cassette sub-family B member 5

Gen-ID: 340273

NCBI Accession: NP_001157413

UniProt: Q2M3G0