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APC1 Antikörper (pSer355)

ANAPC1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Schimpanse WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN401294
  • Target Alle APC1 (ANAPC1) Antikörper anzeigen
    APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))
    Bindungsspezifität
    • 26
    • 16
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 351-359, pSer355
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Schimpanse
    Wirt
    • 80
    • 1
    Kaninchen
    Klonalität
    • 80
    • 1
    Polyklonal
    Konjugat
    • 32
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser APC1 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 40
    • 32
    • 15
    • 14
    • 13
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody is specific for phosphorylated APC1 protein at the pS355 residue.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Bovine, Chimpanzee, Chicken.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Immunogen
    Synthetic peptide corresponding to amino acids 351-359 of Human Apc1 protein
    Isotyp
    IgG
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  • Applikationshinweise
    ELISA: 1/10,000 - 1/40,000. Western Blot: 1/200 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.55 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
  • Target
    APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))
    Andere Bezeichnung
    APC1 / ANAPC1 (ANAPC1 Produkte)
    Synonyme
    APC1 antikoerper, MCPR antikoerper, TSG24 antikoerper, DDBDRAFT_0186456 antikoerper, DDBDRAFT_0234263 antikoerper, DDB_0186456 antikoerper, DDB_0234263 antikoerper, 2610021O03Rik antikoerper, AI047775 antikoerper, AI853536 antikoerper, AW547281 antikoerper, Apc1 antikoerper, Mcpr antikoerper, tsg24 antikoerper, EMBRYO DEFECTIVE 2771 antikoerper, MOP10.10 antikoerper, MOP10_10 antikoerper, anaphase promoting complex subunit 1 antikoerper, E3 ubiquitin ligase antikoerper, ANAPC1 antikoerper, Anapc1 antikoerper, CC1G_09696 antikoerper, anapc1 antikoerper, EMB2771 antikoerper
    Hintergrund
    APC1 (also known as Anaphase promoting complex subunit 1, Cyclosome subunit 1, Protein Tsg24, Mitotic checkpoint regulator and ANAPC1) is 1 of at least 11 subunits of the anaphase-promoting complex (APC), which functions at the metaphase-to-anaphase transition of the cell cycle and is regulated by spindle checkpoint proteins. The APC is an E3 ubiquitin ligase that targets cell cycle regulatory proteins for degradation by the proteasome, thereby allowing progression through the cell cycle.Synonyms: Anaphase-promoting complex subunit 1, Cyclosome subunit 1, MCPR, Mitotic checkpoint regulator, TSG24, Testis-specific gene 24 protein
    Gen-ID
    64682
    NCBI Accession
    NP_073153
    UniProt
    Q9H1A4
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