RAD23B Antikörper (AA 163-176)

Produktnummer ABIN401177

Produktdetails anti-RAD23B Antikörper

Target: RAD23B (RAD23 Homolog B (RAD23B))

Bindungsspezifität: AA 163-176

Reaktivität: Human, Hund, Saccharomyces cerevisiae, Schimpanse

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser RAD23B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: Reactivity occurs against Human HR23B protein. Cross reactivity with HR23B protein from Mouse and Rat may also occur as sequence homology varies by one amino acid residue in this sequence by BLAST analysis. Reactivity with HR23B protein from other sources is not known.

Kreuzreaktivität (Details): Species reactivity (expected):Canine, Chimpanzee, S.cerevisiae.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase

Immunogen: Synthetic peptide corresponding aa 163-176 of human HR23B protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA: 1/2000 - 1/10000. Western Blot: 1/500 - 1/2000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.1 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide, None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Andere Bezeichnung: RAD23B (RAD23B Produkte)

Synonyme: HHR23B antikoerper, HR23B antikoerper, P58 antikoerper, 0610007D13Rik antikoerper, AV001138 antikoerper, mHR23B antikoerper, p58 antikoerper, MGC107846 antikoerper, zgc:65951 antikoerper, RAD23 homolog B, nucleotide excision repair protein antikoerper, UV excision repair protein RAD23 homolog B antikoerper, RAD23 homolog B, nucleotide excision repair protein S homeolog antikoerper, RAD23B antikoerper, Rad23b antikoerper, rd23b antikoerper, rad23b antikoerper, rad23b.S antikoerper

Hintergrund: HR23B (also known as UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa protein and p58) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.Synonyms: HR23B, UV excision repair protein RAD23 homolog B, XP-C repair-complementing complex 58 kDa protein

Gen-ID: 5887

NCBI Accession: NP_002865

UniProt: P54727

Pathways: DNA Reparatur