CCL3L1 Antikörper

Produktnummer ABIN401068

Produktdetails anti-CCL3L1 Antikörper

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Reaktivität: Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL3L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to CCL3L1.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Recombinant protein raised in yeast, corresponding to the 70 amino acids of the mature swine CCL3L1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1,0 μg/mL. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 0.1 mL of deionized water (or equivalent).

Konzentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CCL3L1

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Andere Bezeichnung: LD78 beta / CCL3L1 (CCL3L1 Produkte)

Synonyme: 464.2 antikoerper, D17S1718 antikoerper, G0S19-2 antikoerper, LD78 antikoerper, LD78BETA antikoerper, MIP1AP antikoerper, SCYA3L antikoerper, SCYA3L1 antikoerper, C-C motif chemokine ligand 3 like 1 antikoerper, chemokine (C-C motif) ligand 3-like 1 antikoerper, CCL3L1 antikoerper

Hintergrund: Chemokine (C-C motif) ligand 3-like 1 (CCL3L1), also known as macrophage inflammatory protein 1 alpha (MIP-1 alpha, other synonyms: ld78beta, scya3l1, small inducible cytokine a3-like 1), is a member of the CC or beta chemokine subfamily that was originally purified from the conditioned media of an LPS-stimulated murine macrophage cell line. In humans, CCL3L1 is encoded by a variable copy-number gene. The CC family induces MCP1 and RANTES, and exhibits a variety of proinflammatory activities including chemotaxis, and functional and proliferative activation of leukocytes, lymphocytes, and macrophages. Its signal is transmitted through transmembrane receptors, CC chemokine receptors, CCR1, CCR3 and CCR5. CCL3L1/MIP-1 alpha acts as a chemoattractant to a variety of cells including monocytes, T cells, B cells and eosinophils. CCL3L1 binds to several chemokine receptors. In humans these receptors include chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. In swine, CCL3L1 protein is 86 % similar to CCL4 protein, and 73 % similar to CCL5.Synonyms: C-C motif chemokine 3-like 1, D17S1718, G0/G1 switch regulatory protein 19-2, G0S19-2, SCYA3L1, Small-inducible cytokine A3-like 1, Tonsillar lymphocyte LD78 beta protein

Gen-ID: 414062

NCBI Accession: NP_001001437

UniProt: P16619

Pathways: Cellular Response to Molecule of Bacterial Origin