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COL18A1 Antikörper (Chain alpha 1)

COL18A1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Maus Monoclonal 1873-46 unconjugated
Produktnummer ABIN400737
  • Target Alle COL18A1 Antikörper anzeigen
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Chain alpha 1
    Reaktivität
    • 77
    • 47
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 78
    • 8
    • 2
    Maus
    Klonalität
    • 79
    • 10
    Monoklonal
    Konjugat
    • 45
    • 9
    • 7
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COL18A1 Antikörper ist unkonjugiert
    Applikation
    • 75
    • 49
    • 32
    • 14
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    Recognizes Mouse Endostatin (Mr 22 kDa), an unidentified protein is also weakly detected (Mr 52 kDa).
    Kreuzreaktivität (Details)
    Species reactivity (expected):Human and Rat.
    Species reactivity (tested):Mouse.
    Produktmerkmale
    Synonyms: COL18A1, Endostatin, KNO1
    Aufreinigung
    Thiophilic Adsorption Chromatography.
    Immunogen
    Full-length Recombinant Murine Endostatin.
    Klon
    1873-46
    Isotyp
    IgG
    Top Product
    Discover our top product COL18A1 Primärantikörper
  • Applikationshinweise
    Western blot (Immunoblot). Immunohistochemistry on Paraffin Sections: 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    50 mM Sodium Phosphate, pH 8.0 containing 0.05 % Sodium Azide, before the addition of Glycerol to 30 %.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))
    Abstract
    COL18A1 Produkte
    Synonyme
    KNO antikoerper, KNO1 antikoerper, KS antikoerper, cb371 antikoerper, cb529 antikoerper, fc96d06 antikoerper, sb:cb529 antikoerper, wu:fb47h10 antikoerper, wu:fb77g12 antikoerper, wu:fc50f04 antikoerper, wu:fc96d06 antikoerper, wu:fk02h12 antikoerper, kno antikoerper, kno1 antikoerper, collagen type XVIII alpha 1 chain antikoerper, collagen type XVIII alpha 1 chain a antikoerper, collagen, type XVIII, alpha 1 antikoerper, collagen type XVIII alpha 1 antikoerper, COL18A1 antikoerper, col18a1a antikoerper, Col18a1 antikoerper, col18a1 antikoerper
    Hintergrund
    Endostatin (20-22 kDa), a cleaved product of the C-terminal domain of collagen XVIII, is an endogenous angiogenesis inhibitor. It was originally found in conditioned media from a murine endothelial tumor cell line, hemangioendothelioma. Endostatin inhibits endothelial cell migration (in vivo and in vitro) and induces endothelial cell apoptosis. It inhibits tumor growth and impairs blood vessel maturation in wound healing. Endostatin has an important role in endothelial cell adhesion and cytoskeletal organization. Endostatin can be found in vessel walls (elastic fibers) and basement membranes.Synonyms: COL18A1, Endostatin, KNO1
    Gen-ID
    80781
    UniProt
    P39060
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