CNPase (CNP) Antikörper

Antigen: CNPase (CNP)

Synonyme: CNP1, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, CNP, sb:cb662, wu:fd44a05, wu:fi35d08, si:ch73-158e11.4, DKFZp469F1421

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: ELISA, Western Blot (WB)

Produktnummer: ABIN398825

Produktbeschreibung

Weitere Bezeichnung: CNPase

Format: Affinity-purified

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: CNPase (2, 3-cyclic nucleotide 3-phosphodiesterase) is a membrane-bound enzyme that can links tubulin to membranes and may regulate cytoplasmic microtubule distribution. The enzyme itself exists itself in two forms due to alternative splicing and is abundantly present in brain and peripheral nerve. CNPase has been very useful as a marker for these particular cell types including oligodendrocytes and Schwann cells. Expression of CNPase may be severely reduced in many diseases such as multiple sclerosis.Antibodies-Online Rabbit Anti-CNPase Polyclonal Antibody is developed in rabbit using a synthetic KLH-coupled peptide from within carboxyl terminus of human CNPase (Swiss Prot: P09543).

Spezifität: Antibodies-Online Rabbit Anti-CNPase Polyclonal Antibody detects endogenous levels of Human mouse and rat CNPase.

Anwendungen

Applikationshinweise: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.ELISA: 0.05-0.2 ug/mlWestern blot: 0.5-1 ug/mlOther Applications: user-optimized

Konzentration: 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.

Reinigung: Immunoaffinity chromatography

Lagerung: Rabbit Anti-CNPase Polyclonal Antibody should be stored lyophilized until use. It remains stable in lyophilized form for at least two years if stored at -20°C or below. The reconstituted antibody can be stored for two to three weeks at 2-8°C or for up to 12 months at -20°C or below. Avoid repeated freeze and thaw cycles.

Forschungsgebiet: Neurologie, Glia Marker

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of lysates using 1 ug/ml Rabbit Anti-CNPase Polyclonal Antibody (Antibodies-Online, ABIN398825)The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.