Occludin Antikörper (OCLN) (AA 423-523)

Details for Product anti-OCLN Antibody No. ABIN395206, Anbieter: Anmelden zum Anzeigen
Antigen
  • tpmt
  • OCLN
  • BLCPMG
  • AI503564
  • Ocl
  • ocln
  • oclnb
  • wu:fd23h10
  • wu:fi13c01
  • zgc:113992
  • zgc:56359
  • occludin
  • occludin a
  • OCLN
  • ocln
  • Ocln
  • ocln-b
  • oclna
Alternativen
anti-Human Occludin Antikörper für ELISA
Epitop
AA 423-523
34
15
13
7
6
6
5
5
4
4
3
3
2
2
1
1
Reaktivität
Human
111
56
50
17
17
4
4
4
3
2
2
2
Wirt
Maus
86
29
3
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser Occludin Antikörper ist unkonjugiert
6
6
5
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Western Blotting (WB)
100
55
28
25
22
13
10
7
3
1
1
1
Optionen
Hersteller
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Immunogen OCLN (NP_002529, 423 a.a. ~ 523 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Klon 1G7
Isotyp IgG1 kappa
Spezifität OCLN (NP_002529, 423 a.a. ~ 523 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Reinigung This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Andere Bezeichnung OCLN (OCLN Antibody Abstract)
Hintergrund Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molekulargewicht 59144 DA
Gen-ID 12406
NCBI Accession NP_002529
Forschungsgebiet Cell Structure
Pathways Cell-Cell Junction Organization, Hepatitis C
Applikationshinweise Western blot = 1:500-1000
Kommentare

Background: This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described.

Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer PBS with 0.09% (w/v) sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Occludin Antikörper (OCLN) (AA 423-523) (ABIN395206) Immunofluorescence of monoclonal antibody to OCLN on HeLa cell (antibody concentratio...
Immunohistochemistry (IHC) image for anti-Occludin Antikörper (OCLN) (AA 423-523) (ABIN395206) anti-Occludin (OCLN) (AA 423-523) antibody (Image 2)
Allgemeine Veröffentlichungen Raikwar, Vandewalle, Thomas: "Nedd4-2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia." in: American journal of physiology. Renal physiology, Vol. 299, Issue 2, pp. F436-44, 2010 (PubMed).

Kohaar, Ploss, Korol, Mu, Schoggins, OBrien, Rice, Prokunina-Olsson: "Splicing diversity of the human OCLN gene and its biological significance for hepatitis C virus entry." in: Journal of virology, Vol. 84, Issue 14, pp. 6987-94, 2010 (PubMed).

Raleigh, Marchiando, Zhang, Shen, Sasaki, Wang, Long, Turner: "Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions." in: Molecular biology of the cell, Vol. 21, Issue 7, pp. 1200-13, 2010 (PubMed).

Du, Xu, Yu, Zhang, Lu, Yuan, Huang, Zhang, Bao, Jia, Wu, Zhu, Zhang, Zhang, Chen: "The tight junction protein, occludin, regulates the directional migration of epithelial cells." in: Developmental cell, Vol. 18, Issue 1, pp. 52-63, 2010 (PubMed).

Steed, Rodrigues, Balda, Matter: "Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family." in: BMC cell biology, Vol. 10, pp. 95, 2010 (PubMed).