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DUSP10 Antikörper (N-Term)

DUSP10 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB5879 unconjugated
Produktnummer ABIN392871
  • Target Alle DUSP10 Antikörper anzeigen
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    Bindungsspezifität
    • 15
    • 10
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 52
    • 29
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 48
    • 3
    • 1
    Kaninchen
    Klonalität
    • 50
    • 2
    Polyklonal
    Konjugat
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP10 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 29
    • 18
    • 13
    • 13
    • 8
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DUSP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DUSP10.
    Klon
    RB5879
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DUSP10 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
    Andere Bezeichnung
    DUSP10 (DUSP10 Produkte)
    Synonyme
    DUSP10 antikoerper, MKP-5 antikoerper, MKP5 antikoerper, 2610306G15Rik antikoerper, AI158871 antikoerper, Mkp-5 antikoerper, Mkp5 antikoerper, dual specificity phosphatase 10 antikoerper, DUSP10 antikoerper, Dusp10 antikoerper
    Hintergrund
    Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique, it is evenly distributed in both the cytoplasm and the nucleus. The protein is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli.
    Molekulargewicht
    52642
    Gen-ID
    11221
    NCBI Accession
    NP_009138, NP_653329, NP_653330
    UniProt
    Q9Y6W6
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