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ULK2 Antikörper (N-Term)

ULK2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB12561 unconjugated
Produktnummer ABIN392692
  • Target Alle ULK2 Antikörper anzeigen
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    Bindungsspezifität
    • 12
    • 11
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-264, N-Term
    Reaktivität
    • 73
    • 18
    • 8
    Human
    Wirt
    • 65
    • 9
    Kaninchen
    Klonalität
    • 66
    • 8
    Polyklonal
    Konjugat
    • 35
    • 8
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ULK2 Antikörper ist unkonjugiert
    Applikation
    • 58
    • 50
    • 15
    • 15
    • 14
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ULK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-264 amino acids from the N-terminal region of human ULK2.
    Klon
    RB12561
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ULK2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    ULK2 (Unc-51 Like Kinase 2 (ULK2))
    Andere Bezeichnung
    ULK2 (ULK2 Produkte)
    Synonyme
    ULK2 antikoerper, ATG1B antikoerper, Unc51.2 antikoerper, A830085I22Rik antikoerper, AU015340 antikoerper, mKIAA0623 antikoerper, unc-51 like autophagy activating kinase 2 antikoerper, unc-51 like kinase 2 antikoerper, ULK2 antikoerper, Ulk2 antikoerper, ulk2 antikoerper
    Hintergrund
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). Two human homologs of the yeast autophagy-specific kinase exist: ULK1(APG1) and ULK2. APG1 plays a critical role in regulating key elements of the autophagy pathway. APG1 stimulates autophagy, leading to autophagy-dependent restriction of cell growth and ultimately cell apoptosis at high levels of activity, and is a negative regulator of mTOR signaling.
    Molekulargewicht
    112694
    Gen-ID
    9706
    NCBI Accession
    NP_001136082, NP_055498
    UniProt
    Q8IYT8
    Pathways
    Regulation of Cell Size, Autophagie
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