This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This B-RAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-453 amino acids from the Central region of human B-RAF.
B-raf antikoerper, HYPT11 antikoerper, SME antikoerper, Sm-E antikoerper, b-raf antikoerper, sm-e antikoerper, sme antikoerper, SmE antikoerper, snRNP-E antikoerper, AL022645 antikoerper, C76690 antikoerper, zgc:56682 antikoerper, small nuclear ribonucleoprotein polypeptide E antikoerper, small nuclear ribonucleoprotein polypeptide E L homeolog antikoerper, small nuclear ribonucleoprotein E antikoerper, SNRPE antikoerper, snrpe.L antikoerper, Snrpe antikoerper, snrpe antikoerper
Hintergrund
BRAF, a mebmer of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.