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DDR1 Antikörper (N-Term)

DDR1 Reaktivität: Human, Ratte WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB01477 unconjugated
Produktnummer ABIN392014
  • Target Alle DDR1 Antikörper anzeigen
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Bindungsspezifität
    • 20
    • 15
    • 9
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-47, N-Term
    Reaktivität
    • 89
    • 43
    • 42
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Human, Ratte
    Wirt
    • 93
    • 11
    Kaninchen
    Klonalität
    • 92
    • 11
    • 1
    Polyklonal
    Konjugat
    • 50
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser DDR1 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 43
    • 26
    • 26
    • 24
    • 13
    • 11
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This DDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human DDR1.
    Klon
    RB01477
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DDR1 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    Andere Bezeichnung
    DDR1 (DDR1 Produkte)
    Synonyme
    CG11573 antikoerper, CG13984 antikoerper, CG13985 antikoerper, CG33531 antikoerper, CG9488 antikoerper, CG9490 antikoerper, CT33540 antikoerper, DDR antikoerper, Dmel\\CG33531 antikoerper, Dmel_CG13984 antikoerper, 6030432F18 antikoerper, AI323681 antikoerper, CD167a antikoerper, Cak antikoerper, Nep antikoerper, PTK3A antikoerper, CAK antikoerper, CD167 antikoerper, EDDR1 antikoerper, HGK2 antikoerper, MCK10 antikoerper, NEP antikoerper, NTRK4 antikoerper, PTK3 antikoerper, RTK6 antikoerper, TRKE antikoerper, Drd1 antikoerper, PTK3D antikoerper, Discoidin domain receptor antikoerper, discoidin domain receptor family, member 1 antikoerper, discoidin domain receptor tyrosine kinase 1 antikoerper, Ddr antikoerper, Ddr1 antikoerper, DDR1 antikoerper
    Hintergrund
    Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. The gene is located on chromosome 6p21.3 in proximity to several HLA class I genes.
    Molekulargewicht
    101128
    Gen-ID
    780
    NCBI Accession
    NP_001189450, NP_001189451, NP_001189452, NP_001945, NP_054699, NP_054700
    UniProt
    Q08345
    Pathways
    RTK Signalweg, Smooth Muscle Cell Migration
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