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EPH Receptor B2 Antikörper (C-Term)

EPHB2 Reaktivität: Human WB, IHC (p), IF Wirt: Kaninchen Polyclonal RB01652 unconjugated
Produktnummer ABIN391920
  • Target Alle EPH Receptor B2 (EPHB2) Antikörper anzeigen
    EPH Receptor B2 (EPHB2)
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1021-1050, C-Term
    Reaktivität
    • 69
    • 30
    • 13
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 53
    • 16
    • 5
    • 2
    Kaninchen
    Klonalität
    • 55
    • 21
    Polyklonal
    Konjugat
    • 37
    • 8
    • 7
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPH Receptor B2 Antikörper ist unkonjugiert
    Applikation
    • 55
    • 53
    • 35
    • 15
    • 14
    • 10
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This EphB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1021-1050 amino acids from the C-terminal region of human EphB2.
    Klon
    RB01652
    Isotyp
    Ig Fraction
  • Applikationshinweise
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    EPH Receptor B2 (EPHB2)
    Andere Bezeichnung
    EphB2 (EPHB2 Produkte)
    Synonyme
    CAPB antikoerper, DRT antikoerper, EK5 antikoerper, EPHT3 antikoerper, ERK antikoerper, Hek5 antikoerper, PCBC antikoerper, Tyro5 antikoerper, ERK2 antikoerper, ERT1 antikoerper, MAPK2 antikoerper, P42MAPK antikoerper, PRKM1 antikoerper, PRKM2 antikoerper, p38 antikoerper, p40 antikoerper, p41 antikoerper, p41mapk antikoerper, RGD1564232 antikoerper, Cek5 antikoerper, Drt antikoerper, ETECK antikoerper, Erk antikoerper, Nuk antikoerper, Prkm5 antikoerper, Qek5 antikoerper, Sek3 antikoerper, cek5 antikoerper, ephb2 antikoerper, xEphB2 antikoerper, si:ch73-160e9.1 antikoerper, tpx2 antikoerper, wu:fb09e10 antikoerper, wu:fc64a03 antikoerper, wu:fi18g12 antikoerper, zgc:112296 antikoerper, EPH receptor B2 antikoerper, mitogen-activated protein kinase 1 antikoerper, Eph receptor B2 antikoerper, EPH receptor B2 L homeolog antikoerper, eph receptor B2a antikoerper, eph receptor B2b antikoerper, EPHB2 antikoerper, MAPK1 antikoerper, Ephb2 antikoerper, ephb2.L antikoerper, ephb2a antikoerper, ephb2b antikoerper
    Hintergrund
    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ligand-activated form of EphB2, which belongs to the Tyr family of protein kinases, interacts with multiple proteins, including GTPase-activating protein (RASGAP) through its SH2 domain. It binds RASGAP through the juxtamembrane tyrosines residues, and also interacts with PRKCABP and GRIP1 This type I membrane protein is expressed in brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. It is preferentially expressed in fetal brain. This protein contains putatively 2 fibronectin type III domains and 1 sterile alpha motif (SAM) domain.
    Molekulargewicht
    117493
    Gen-ID
    2048
    NCBI Accession
    NP_004433, NP_059145
    UniProt
    P29323
    Pathways
    RTK Signalweg, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteine
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