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CDK10 Antikörper (N-Term)

CDK10 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB3172 unconjugated
Produktnummer ABIN391741
  • Target Alle CDK10 Antikörper anzeigen
    CDK10 (Cyclin-Dependent Kinase 10 (CDK10))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-32, N-Term
    Reaktivität
    • 65
    • 17
    • 14
    • 1
    • 1
    • 1
    Human
    Wirt
    • 62
    • 2
    • 1
    Kaninchen
    Klonalität
    • 65
    Polyklonal
    Konjugat
    • 24
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDK10 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 34
    • 18
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CDK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-32 amino acids from the N-terminal region of human CDK10.
    Klon
    RB3172
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CDK10 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Hong, Zhang, You, Qiu, Giuliano, Cui, Zhang, Cui: "Elevated C1orf63 expression is correlated with CDK10 and predicts better outcome for advanced breast cancers: a retrospective study." in: BMC cancer, Vol. 15, pp. 548, (2015) (PubMed).

    You, Li, Qin, Zhang, Song, Ran, Gao: "Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report." in: Cellular oncology (Dordrecht), Vol. 38, Issue 6, pp. 485-91, (2015) (PubMed).

    Leman, Magheli, Yong, Netto, Hinz, Getzenberg: "Identification of nuclear structural protein alterations associated with seminomas." in: Journal of cellular biochemistry, Vol. 108, Issue 6, pp. 1274-9, (2009) (PubMed).

    Iorns, Turner, Elliott, Syed, Garrone, Gasco, Tutt, Crook, Lord, Ashworth: "Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer." in: Cancer cell, Vol. 13, Issue 2, pp. 91-104, (2008) (PubMed).

  • Target
    CDK10 (Cyclin-Dependent Kinase 10 (CDK10))
    Andere Bezeichnung
    CDK10 (CDK10 Produkte)
    Synonyme
    PISSLRE antikoerper, BC017131 antikoerper, zgc:110252 antikoerper, DDBDRAFT_0216532 antikoerper, DDBDRAFT_0229427 antikoerper, DDB_0216532 antikoerper, DDB_0229427 antikoerper, cdc2rk antikoerper, NV16107 antikoerper, cyclin dependent kinase 10 antikoerper, cyclin-dependent kinase 10 antikoerper, CDK family protein kinase antikoerper, hypothetical protein antikoerper, cyclin-dependent kinase 10 L homeolog antikoerper, CDK10 antikoerper, Cdk10 antikoerper, cdk10 antikoerper, LOC5566134 antikoerper, cdk10.L antikoerper
    Hintergrund
    CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation. Its function is limited to cell cycle G2-M phase.
    Molekulargewicht
    41038
    Gen-ID
    8558
    NCBI Accession
    NP_001092003, NP_001153839, NP_443713, NP_443714
    UniProt
    Q15131
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