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CAMKII gamma Antikörper (C-Term)

CAMK2G Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1246 unconjugated
Produktnummer ABIN391313
  • Target Alle CAMKII gamma (CAMK2G) Antikörper anzeigen
    CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))
    Bindungsspezifität
    • 12
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 309-338, C-Term
    Reaktivität
    • 68
    • 61
    • 45
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 53
    • 32
    • 1
    Kaninchen
    Klonalität
    • 48
    • 38
    Polyklonal
    Konjugat
    • 40
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser CAMKII gamma Antikörper ist unkonjugiert
    Applikation
    • 57
    • 36
    • 32
    • 26
    • 22
    • 15
    • 11
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CAMK2G (CAMK2 gamma) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-338 amino acids from the C-terminal region of human CAMK2G (CAMK2 gamma).
    Klon
    RB1246
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000. WB: 1:500-1000. WB: 1:500. WB: 1:2000. IHC-P: 1:50~100. WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Jiang, Wu, Lu, Zhang, Yu, Gan, Wu, Xu, Zheng, Zhang, Xu, Ma, Gan, Huang, Yu, Huang, Xu: "Activation of CaMKIIγ potentiates T-cell acute lymphoblastic leukemia leukemogenesis via phosphorylating FOXO3a." in: Oncotarget, Vol. 8, Issue 43, pp. 75050-75064, (2017) (PubMed).

  • Target
    CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))
    Andere Bezeichnung
    CAMK2G (CAMK2 gamma) (CAMK2G Produkte)
    Synonyme
    CAMK antikoerper, CAMK-II antikoerper, CAMKG antikoerper, 5930429P18Rik antikoerper, Camkg antikoerper, calcium/calmodulin dependent protein kinase II gamma antikoerper, calcium/calmodulin-dependent protein kinase II gamma antikoerper, CAMK2G antikoerper, Camk2g antikoerper
    Hintergrund
    CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
    Molekulargewicht
    62607
    Gen-ID
    818
    NCBI Accession
    NP_001213, NP_751909, NP_751913
    UniProt
    Q13555
    Pathways
    WNT Signalweg, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity
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