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PDXK Antikörper (C-Term)

PDXK Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB5462 unconjugated
Produktnummer ABIN391248
  • Target Alle PDXK Antikörper anzeigen
    PDXK (Pyridoxal Kinase (PDXK))
    Bindungsspezifität
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 242-272, C-Term
    Reaktivität
    • 49
    • 32
    • 21
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 7
    Kaninchen
    Klonalität
    • 47
    • 5
    Polyklonal
    Konjugat
    • 28
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PDXK Antikörper ist unkonjugiert
    Applikation
    • 50
    • 19
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PDXK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-272 amino acids from the C-terminal region of human PDXK.
    Klon
    RB5462
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PDXK Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    PDXK (Pyridoxal Kinase (PDXK))
    Andere Bezeichnung
    PDXK (PDXK Produkte)
    Synonyme
    C21orf124 antikoerper, C21orf97 antikoerper, PKH antikoerper, PNK antikoerper, 2310036D04Rik antikoerper, AA119688 antikoerper, C77999 antikoerper, Pdxk antikoerper, PSPTO5521 antikoerper, DDBDRAFT_0190079 antikoerper, DDBDRAFT_0191114 antikoerper, DDB_0190079 antikoerper, DDB_0191114 antikoerper, ATSOS4 antikoerper, K18L3.1 antikoerper, K18L3_1 antikoerper, SALT OVERLY SENSITIVE 4 antikoerper, pdxk antikoerper, si:dkey-263m10.2 antikoerper, si:dz69g10.1 antikoerper, cb1056 antikoerper, pdxkl antikoerper, si:dkey-281i8.2 antikoerper, wu:fa55a03 antikoerper, wu:fb10c12 antikoerper, zgc:101900 antikoerper, pyridoxal kinase antikoerper, pyridoxal (pyridoxine, vitamin B6) kinase antikoerper, Pyridoxal kinase antikoerper, pfkB-like carbohydrate kinase family protein antikoerper, pyridoxal (pyridoxine, vitamin B6) kinase b antikoerper, pyridoxal (pyridoxine, vitamin B6) kinase a antikoerper, PDXK antikoerper, Pdxk antikoerper, pdxY antikoerper, pdxK antikoerper, Bphyt_1541 antikoerper, pykA antikoerper, Kfla_4736 antikoerper, Kvar_1290 antikoerper, Mrub_2507 antikoerper, BC1002_1103 antikoerper, Fbal_1661 antikoerper, Lbys_0710 antikoerper, Intca_0131 antikoerper, Deima_3190 antikoerper, Mesop_1158 antikoerper, LOC100283562 antikoerper, pdxk antikoerper, SOS4 antikoerper, pdxkb antikoerper, pdxka antikoerper
    Hintergrund
    Pyridoxal kinase (PDXK) converts vitamin B6 to pyridoxal-5-phosphate (PLP), an essential cofactor in the intermediate metabolism of amino acids and neurotransmitters. The PDXK gene encodes a 312-amino acid polypeptide, and expression of the cDNA reveals pyridoxal kinase activity. Northern blot analysis revealed that a major 1.5-kb PDXK transcript is expressed in all tissues tested. The expression of PDXK shows circadian oscillations. The expression of Pdxk in mouse liver and brain is regulated by the 3 PAR bZIP transcription factors, Dbp, Hlf, and Tef, which also show circadian oscillations in expression. Mice devoid of all 3 transcription factors show decreased levels of brain PLP, serotonin, and dopamine, and are highly susceptible to frequently lethal generalized spontaneous and audiogenic epilepsies.
    Molekulargewicht
    35102
    Gen-ID
    8566
    NCBI Accession
    NP_003672
    UniProt
    O00764
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