MARK4 Antikörper (C-Term)

Produktnummer ABIN391222

Produktdetails anti-MARK4 Antikörper

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Bindungsspezifität: AA 611-641, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MARK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-641 amino acids from the C-terminal region of human MARK4.

Klon: RB5447

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MARK4

Target: MARK4 (MAP/microtubule Affinity-Regulating Kinase 4 (MARK4))

Andere Bezeichnung: MARK4 (MARK4 Produkte)

Synonyme: MARK4 antikoerper, MARK4L antikoerper, MARK4S antikoerper, MARKL1 antikoerper, MARKL1L antikoerper, PAR-1D antikoerper, 2410090P21Rik antikoerper, C79806 antikoerper, Markl1 antikoerper, microtubule affinity regulating kinase 4 antikoerper, MAP/microtubule affinity regulating kinase 4 antikoerper, MARK4 antikoerper, Mark4 antikoerper

Hintergrund: MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1-associated kinase domain. RT-PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6-kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony-forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells.

Molekulargewicht: 82520

Gen-ID: 57787

NCBI Accession: NP_001186796, NP_113605

UniProt: Q96L34