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Ketohexokinase Antikörper (C-Term)

KHK Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB05412 unconjugated
Produktnummer ABIN391089
  • Target Alle Ketohexokinase (KHK) Antikörper anzeigen
    Ketohexokinase (KHK)
    Bindungsspezifität
    • 15
    • 13
    • 10
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 251-281, C-Term
    Reaktivität
    • 77
    • 34
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 72
    • 4
    • 1
    Kaninchen
    Klonalität
    • 74
    • 3
    Polyklonal
    Konjugat
    • 31
    • 7
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Ketohexokinase Antikörper ist unkonjugiert
    Applikation
    • 64
    • 39
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This Ketohexokinase (KHK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-281 amino acids from the C-terminal region of human Ketohexokinase (KHK).
    Klon
    RB05412
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product KHK Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Springer, Lindbloom-Hawley, Schermerhorn: "Tissue expression of ketohexokinase in cats." in: Research in veterinary science, Vol. 87, Issue 1, pp. 115-7, (2009) (PubMed).

    Diggle, Shires, Leitch, Brooke, Carr, Markham, Hayward, Asipu, Bonthron: "Ketohexokinase: expression and localization of the principal fructose-metabolizing enzyme." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 57, Issue 8, pp. 763-74, (2009) (PubMed).

  • Target
    Ketohexokinase (KHK)
    Abstract
    KHK Produkte
    Synonyme
    wu:fj68h03 antikoerper, zgc:92219 antikoerper, zgc:92626 antikoerper, KHK antikoerper, khk antikoerper, KETHPRO antikoerper, ketohexokinase antikoerper, Ketohexokinase antikoerper, KHK antikoerper, khk antikoerper, Hhal_0921 antikoerper, AaeL_AAEL006316 antikoerper, Nwat_0240 antikoerper, Khk antikoerper
    Hintergrund
    Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.
    Molekulargewicht
    32523
    Gen-ID
    3795
    NCBI Accession
    NP_000212, NP_006479
    UniProt
    P50053
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