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PRKAB2 Antikörper (N-Term)

PRKAB2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB3183 unconjugated
Produktnummer ABIN391055
  • Target Alle PRKAB2 Antikörper anzeigen
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    Bindungsspezifität
    • 13
    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-33, N-Term
    Reaktivität
    • 41
    • 20
    • 11
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 30
    • 10
    • 1
    Kaninchen
    Klonalität
    • 34
    • 7
    Polyklonal
    Konjugat
    • 30
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser PRKAB2 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 24
    • 20
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This AMPK beta2 (PRKAB2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human AMPK beta2 (PRKAB2).
    Klon
    RB3183
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PRKAB2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    Andere Bezeichnung
    AMPK Beta2 (PRKAB2) (PRKAB2 Produkte)
    Synonyme
    prkab2 antikoerper, MGC64365 antikoerper, PRKAB2 antikoerper, DKFZp469M1118 antikoerper, 5730553K21Rik antikoerper, AW049591 antikoerper, BB124140 antikoerper, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog antikoerper, protein kinase AMP-activated non-catalytic subunit beta 2 antikoerper, protein kinase, AMP-activated, beta 2 non-catalytic subunit antikoerper, prkab2.L antikoerper, PRKAB2 antikoerper, prkab2 antikoerper, Prkab2 antikoerper
    Hintergrund
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
    Molekulargewicht
    30302
    Gen-ID
    5565
    NCBI Accession
    NP_005390
    UniProt
    O43741
    Pathways
    AMPK Signaling, Warburg Effekt
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