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LATS2 Antikörper (AA 228-258)

LATS2 Reaktivität: Human IHC (p) Wirt: Kaninchen Polyclonal RB3032 unconjugated
Produktnummer ABIN391034
  • Target Alle LATS2 Antikörper anzeigen
    LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
    Bindungsspezifität
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 228-258
    Reaktivität
    • 64
    • 55
    • 15
    • 4
    Human
    Wirt
    • 71
    • 2
    Kaninchen
    Klonalität
    • 71
    • 2
    Polyklonal
    Konjugat
    • 20
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    Dieser LATS2 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 31
    • 13
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This LATS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the Central region of human LATS2.
    Klon
    RB3032
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product LATS2 Primärantikörper
  • Applikationshinweise
    IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Yamashita, Yamamoto, Mimori, Nishida, Takahashi, Haraguchi, Tanaka, Shibata, Sekimoto, Ishii, Doki, Mori: "MicroRNA-372 is associated with poor prognosis in colorectal cancer." in: Oncology, Vol. 82, Issue 4, pp. 205-12, (2012) (PubMed).

  • Target
    LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
    Andere Bezeichnung
    LATS2 (LATS2 Produkte)
    Synonyme
    4932411G09Rik antikoerper, AV277261 antikoerper, AW228608 antikoerper, KPM antikoerper, lats2 antikoerper, large tumor suppressor kinase 2 antikoerper, large tumor suppressor 2 antikoerper, LATS2 antikoerper, Lats2 antikoerper, lats2 antikoerper
    Hintergrund
    LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
    Molekulargewicht
    120136
    Gen-ID
    26524
    NCBI Accession
    NP_055387
    UniProt
    Q9NRM7
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