PRKD3 Antikörper (AA 352-384)

Produktnummer ABIN391014

Produktdetails anti-PRKD3 Antikörper

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Bindungsspezifität: AA 352-384

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PKC-nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-384 amino acids from human PKC-nu.

Klon: RB1047

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-PRKD3 Antikörper (ABIN391014)

Chen, Deng, Singh, Wang: "Protein kinase D3 (PKD3) contributes to prostate cancer cell growth and survival through a PKCepsilon/PKD3 pathway downstream of Akt and ERK 1/2." in: Cancer research, Vol. 68, Issue 10, pp. 3844-53, (2008) (PubMed).

Details zu PRKD3

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Andere Bezeichnung: PKC nu (PRKD3 Produkte)

Synonyme: EPK2 antikoerper, PKC-NU antikoerper, PKD3 antikoerper, PRKCN antikoerper, nPKC-NU antikoerper, PRKD3 antikoerper, 4930557O20Rik antikoerper, 5730497N19Rik antikoerper, Pkcnu antikoerper, Prkcn antikoerper, protein kinase D3 antikoerper, PRKD3 antikoerper, prkd3 antikoerper, Prkd3 antikoerper

Hintergrund: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Molekulargewicht: 100471

Gen-ID: 23683

NCBI Accession: NP_005804

UniProt: O94806