G Protein-Coupled Receptor Kinase 4 (GRK4) (C-Term) Antikörper

Antigen: G Protein-Coupled Receptor Kinase 4 (GRK4)

Synonyme: IT11, GPRK4, GRK4a, GPRK2L, GRK, Gprk4, Gprk2l, A830025H08Rik, AMPK, AMPKalpha, DmAMPK alpha, EG:132E8.2, FBgn0023169, Gprk-4, dAMPKa, snf1a, DmelCG3051, CG3051, GRK4, gprk4, gprk4-a, MGC80630, gprk4-b, MGC82127, it11, grk4a, gprk2l, MGC89135

Epitope: C-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC), ELISA

Zertifikate: ISO 9001:2008

Produktnummer: ABIN390987

Produktbeschreibung

Produktmerkmale: Purified Rabbit Polyclonal Antibody (Pab)

Weitere Bezeichnung: GRK4 (C-term)

Gen-ID: 2868

Swiss-Prot: P32298

Immunogen: This GRK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549~578 amino acids from the C-terminal region of human GRK4.

Isotyp: Ig  (Passende Sekundärantikörper)

Beschreibung: Other names: G protein-coupled receptor kinase GRK4

Spezifität: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GRK4.

Molekulargewicht: 66555 DA

Synonyme: IT11, GPRK4, GRK4a, GPRK2L, GRK, Gprk4, Gprk2l, A830025H08Rik, AMPK, AMPKalpha, DmAMPK alpha, EG:132E8.2, FBgn0023169, Gprk-4, dAMPKa, snf1a, DmelCG3051, CG3051, GRK4, gprk4, gprk4-a, MGC80630, gprk4-b, MGC82127, it11, grk4a, gprk2l, MGC89135

Anwendungen

Applikationshinweise: The suggested dilution will be: ELISA~~1:1,000 Western blotting~~1:100~500 Flow cytometry Immunohistochemistry ~~ 1:10~50

Konzentration: 0.25 mg/ml

Reinigung: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Lagerung: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Forschungsgebiet: Phospho-Antikörper, Zelluläre Signaltransduktion, Proteinmodifikationen, Zellzyklus, Transkriptionsfaktoren, Signaltransduktion, Metabolismus, Zellstruktur

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of anti-GRK4 Pab (ABIN390987) in HL60 cell lysate. GRK4 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Formalin-fixed and paraffin-embedded human testis tissue reacted with GRK4 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated.

Publikationen

Publikationen: Villar, Jones, Armando et al.: "G protein-coupled receptor kinase 4 (GRK4) regulates the phosphorylation and function of the dopamine D3 receptor." in: The Journal of biological chemistry, Vol. 284, Issue 32, pp. 21425-34, 2009 (PubMed).