Adrenergic, Beta, Receptor Kinase 1 (ADRB1) (C-Term) Antikörper

Antigen: Adrenergic, Beta, Receptor Kinase 1 (ADRB1)

Synonyme: RHR, B1AR, ADRB1R, BETA1AR, RATB1AR, Grk2, BARK1, GRK-2, GRK2, Bark-1, Adrbk-1, betaARK1, ADRB1, ADRBK1, adrb1, X-Beta1AR, BAR1

Epitope: C-Term

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Western Blot (WB), Immunhistochemie (IHC), ELISA

Zertifikate: ISO 9001:2008

Produktnummer: ABIN390985

Produktbeschreibung

Produktmerkmale: Purified Rabbit Polyclonal Antibody (Pab)

Weitere Bezeichnung: GRK2 (C-term)

Gen-ID: 156

Swiss-Prot: P25098

Immunogen: This GRK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639~669 amino acids from the C-terminal region of human GRK2.

Isotyp: Ig  (Passende Sekundärantikörper)

Beschreibung: Other names: G-protein coupled receptor kinase 2, Beta-adrenergic receptor kinase 1, Beta-ARK-1

Spezifität: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GRK2.

Molekulargewicht: 79667 DA

Anwendungen

Applikationshinweise: The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100

Konzentration: 0.25 mg/ml

Reinigung: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Lagerung: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Forschungsgebiet: Phospho-Antikörper, Zelluläre Signaltransduktion, Proteinmodifikationen, Zellstruktur

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Western blot analysis of anti-GRK2 C-term Pab (ABIN390985) in Ramos cell lysate. GRK2 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated. BC = breast carcinoma. HC = hepatocarcinoma.

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GRK2 Antibody (C-term) (ABIN390985), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated.

Publikationen

Publikationen: Rao, Rapoport, Kim: "Decreased GRK3 but not GRK2 expression in frontal cortex from bipolar disorder patients." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 6, pp. 851-60, 2009 (PubMed).