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SETD8 Antikörper (AA 220-249)

SETD8 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB18964 unconjugated
Produktnummer ABIN390472
  • Target Alle SETD8 Antikörper anzeigen
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    Bindungsspezifität
    • 22
    • 8
    • 7
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 220-249
    Reaktivität
    • 63
    • 22
    • 11
    Human
    Wirt
    • 47
    • 16
    Kaninchen
    Klonalität
    • 46
    • 17
    Polyklonal
    Konjugat
    • 27
    • 8
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SETD8 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 36
    • 23
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    B
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This SETD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human SETD8.
    Klon
    RB18964
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product SETD8 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    SETD8 (SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))
    Andere Bezeichnung
    SETD8 (SETD8 Produkte)
    Synonyme
    KMT5A antikoerper, PR-Set7 antikoerper, SET07 antikoerper, SET8 antikoerper, 2410195B05Rik antikoerper, AA617402 antikoerper, AW536475 antikoerper, PR-SET7 antikoerper, setd8b antikoerper, wu:fc23f12 antikoerper, zgc:171649 antikoerper, Pr-set7 antikoerper, RGD1305893 antikoerper, Setd8 antikoerper, kmt5a antikoerper, kmt5a-a antikoerper, setd8 antikoerper, setd8-a antikoerper, set8a antikoerper, setd8a antikoerper, wu:fj33f02 antikoerper, zgc:153719 antikoerper, lysine methyltransferase 5A antikoerper, lysine methyltransferase 5Ab antikoerper, lysine methyltransferase 5A S homeolog antikoerper, lysine methyltransferase 5Aa antikoerper, KMT5A antikoerper, Kmt5a antikoerper, kmt5ab antikoerper, kmt5a.S antikoerper, kmt5aa antikoerper
    Hintergrund
    SETD8 is a histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20' monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. It is required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. It is also involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.
    Molekulargewicht
    42890
    Gen-ID
    387893
    NCBI Accession
    NP_065115
    UniProt
    Q9NQR1
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