Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

B-Cell Linker Antikörper (AA 150-178)

BLNK Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18883 unconjugated
Produktnummer ABIN390395
  • Target Alle B-Cell Linker (BLNK) Antikörper anzeigen
    B-Cell Linker (BLNK)
    Bindungsspezifität
    • 28
    • 22
    • 17
    • 15
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-178
    Reaktivität
    • 109
    • 75
    • 38
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 112
    • 15
    • 1
    Kaninchen
    Klonalität
    • 107
    • 21
    Polyklonal
    Konjugat
    • 53
    • 8
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    Dieser B-Cell Linker Antikörper ist unkonjugiert
    Applikation
    • 110
    • 52
    • 36
    • 26
    • 25
    • 18
    • 18
    • 8
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This BLNK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the Central region of human BLNK.
    Klon
    RB18883
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product BLNK Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    B-Cell Linker (BLNK)
    Andere Bezeichnung
    BLNK (BLNK Produkte)
    Synonyme
    BLNK antikoerper, blnk antikoerper, MGC147045 antikoerper, BASH antikoerper, Bca antikoerper, Ly-57 antikoerper, Ly57 antikoerper, Lyw-57 antikoerper, SLP-65 antikoerper, AGM4 antikoerper, BLNK-S antikoerper, LY57 antikoerper, SLP65 antikoerper, bca antikoerper, B-cell linker antikoerper, B cell linker antikoerper, BLNK antikoerper, blnk antikoerper, Blnk antikoerper
    Hintergrund
    BLNK is a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in its gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.
    Molekulargewicht
    50466
    Gen-ID
    29760
    NCBI Accession
    NP_001107566, NP_001245369, NP_037446
    UniProt
    Q8WV28
    Pathways
    BCR Signaling
Sie sind hier:
Kundenservice