PARP6 Antikörper (C-Term)

Produktnummer ABIN390249

Produktdetails anti-PARP6 Antikörper

Target: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Bindungsspezifität: AA 553-583, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Parp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-583 amino acids from the C-terminal region of human Parp6.

Klon: RB14167

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PARP6

Target: PARP6 (Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6))

Andere Bezeichnung: Parp6 (PARP6 Produkte)

Synonyme: ARTD17 antikoerper, PARP-6-B1 antikoerper, PARP-6-C antikoerper, pART17 antikoerper, 1700119G14Rik antikoerper, 2310028P13Rik antikoerper, 3110038K10Rik antikoerper, C030013N01Rik antikoerper, PARP-6 antikoerper, RGD1310937 antikoerper, zgc:92798 antikoerper, poly(ADP-ribose) polymerase family member 6 antikoerper, poly (ADP-ribose) polymerase family, member 6 antikoerper, poly(ADP-ribose) polymerase family member 6 S homeolog antikoerper, poly [ADP-ribose] polymerase 6 antikoerper, poly (ADP-ribose) polymerase family, member 6a antikoerper, PARP6 antikoerper, Parp6 antikoerper, parp6 antikoerper, parp6.S antikoerper, LOC100475149 antikoerper, parp6a antikoerper

Hintergrund: Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

Molekulargewicht: 71115

Gen-ID: 56965

NCBI Accession: NP_064599

UniProt: Q2NL67