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MMP14 Antikörper (N-Term)

MMP14 Reaktivität: Human, Maus, Ratte WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB02027 unconjugated
Produktnummer ABIN390138
  • Target Alle MMP14 Antikörper anzeigen
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    Bindungsspezifität
    • 14
    • 13
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 145-174, N-Term
    Reaktivität
    • 94
    • 33
    • 32
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 83
    • 11
    • 1
    Kaninchen
    Klonalität
    • 73
    • 22
    Polyklonal
    Konjugat
    • 51
    • 8
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MMP14 Antikörper ist unkonjugiert
    Applikation
    • 65
    • 47
    • 36
    • 17
    • 13
    • 11
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Homologie
    B, Pig
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the N-terminal region of human MMP14.
    Klon
    RB02027
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MMP14 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. WB: 1:2000. IHC-P: 1:25. FC: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Du, Wang, Tan, Li, Huang, Huang, Yang, Zhang, Wang, Huang, Huang: "Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice." in: Journal of the American Heart Association, Vol. 5, Issue 12, (2017) (PubMed).

    Zhu, Hong, Tripathi, Sehdev, Belkhiri, El-Rifai: "Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells." in: Molecular cancer research : MCR, Vol. 11, Issue 1, pp. 86-94, (2013) (PubMed).

  • Target
    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
    Andere Bezeichnung
    MMP14 (MMP14 Produkte)
    Synonyme
    MMP1 antikoerper, MMP-14 antikoerper, MMP-X1 antikoerper, MT-MMP antikoerper, MT-MMP 1 antikoerper, MT1-MMP antikoerper, MT1MMP antikoerper, MTMMP1 antikoerper, mmp-x1 antikoerper, mt1-mmp antikoerper, mtmmp1 antikoerper, AI325305 antikoerper, MT-MMP-1 antikoerper, sabe antikoerper, Mt1-mmp antikoerper, MT-MMPbeta antikoerper, cb386 antikoerper, sb:cb386 antikoerper, wu:fb72b09 antikoerper, mmp14 antikoerper, matrix metallopeptidase 14 antikoerper, matrix metallopeptidase 14 (membrane-inserted) antikoerper, matrix metallopeptidase 14b (membrane-inserted) antikoerper, matrix metallopeptidase 14a (membrane-inserted) antikoerper, matrix metallopeptidase 14 L homeolog antikoerper, MMP14 antikoerper, mmp14 antikoerper, Mmp14 antikoerper, mmp14b antikoerper, mmp14a antikoerper, mmp14.L antikoerper
    Hintergrund
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.
    Molekulargewicht
    65894
    Gen-ID
    4323
    NCBI Accession
    NP_004986
    UniProt
    P50281
    Pathways
    Autophagie
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