Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
M, Rat
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This ABCB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-746 amino acids from the C-terminal region of human ABCB7.
CG7955 antikoerper, Dmel\\CG7955 antikoerper, dABCB7 antikoerper, GB11034 antikoerper, ABCB7 antikoerper, fc20c02 antikoerper, wu:fc20c02 antikoerper, ABC7 antikoerper, ASAT antikoerper, Atm1p antikoerper, EST140535 antikoerper, AA517758 antikoerper, AU019072 antikoerper, Abc7 antikoerper, ATP binding cassette subfamily B member 7 antikoerper, ATP-binding cassette sub-family B member 7, mitochondrial antikoerper, ATP-binding cassette, sub-family B (MDR/TAP), member 7 antikoerper, ATP-binding cassette sub-family B member 7, mitochondrial-like antikoerper, ABCB7 antikoerper, LOC412749 antikoerper, abcb7 antikoerper, LOC100367778 antikoerper, LOC100467128 antikoerper, Abcb7 antikoerper
Hintergrund
The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.