PABP Antikörper (AA 250-279)

Produktnummer ABIN389462

Produktdetails anti-PABP Antikörper

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Bindungsspezifität: AA 250-279

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PABP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: B, Rat, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PABPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-279 amino acids from the Central region of human PABPC1.

Klon: RB20873

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu PABP

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Andere Bezeichnung: PABPC1 (PABPC1 Produkte)

Synonyme: PAB1 antikoerper, PABP antikoerper, PABP1 antikoerper, PABPC2 antikoerper, PABPL1 antikoerper, Pabp1 antikoerper, PabpI antikoerper, Pabpl1 antikoerper, ePAB antikoerper, Pabp antikoerper, pab1 antikoerper, pabp antikoerper, pabp1 antikoerper, pabpc1 antikoerper, pabpc2 antikoerper, PABPC1 antikoerper, wu:fb16a02 antikoerper, wu:fi19b08 antikoerper, wu:fj12d09 antikoerper, wu:fj61f06 antikoerper, zgc:109879 antikoerper, zgc:77608 antikoerper, poly(A) binding protein cytoplasmic 1 antikoerper, poly(A) binding protein, cytoplasmic 1 antikoerper, poly(A) binding protein, cytoplasmic 1 S homeolog antikoerper, poly(A) binding protein cytoplasmic 1 like antikoerper, poly(A) binding protein, cytoplasmic 1 L homeolog antikoerper, poly(A) binding protein, cytoplasmic 1a antikoerper, poly A binding protein, cytoplasmic 1 b antikoerper, PABPC1 antikoerper, Pabpc1 antikoerper, pabpc1.S antikoerper, pabpc1 antikoerper, PABPC1L antikoerper, pabpc1.L antikoerper, pabpc1a antikoerper, pabpc1b antikoerper

Hintergrund: PABPC1 binds the poly(A) tail of mRNA. It may be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre-mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. PABPC1 can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. It may be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Molekulargewicht: 70671

Gen-ID: 26986

NCBI Accession: NP_002559

UniProt: P11940

Pathways: SARS-CoV-2 Protein Interaktom