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PFDN6 Antikörper (N-Term)

PFDN6 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB17559 unconjugated
Produktnummer ABIN389346
  • Target Alle PFDN6 Antikörper anzeigen
    PFDN6 (Prefoldin Subunit 6 (PFDN6))
    Bindungsspezifität
    • 5
    • 2
    • 1
    AA 6-34, N-Term
    Reaktivität
    • 15
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 15
    Kaninchen
    Klonalität
    • 15
    Polyklonal
    Konjugat
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PFDN6 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Homologie
    B, M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PFDN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human PFDN6.
    Klon
    RB17559
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product PFDN6 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Tashiro, Zako, Muto, Itoo, Sörgjerd, Terada, Abe, Miyazawa, Kitamura, Kitaura, Kubota, Maeda, Momoi, Iguchi-Ariga, Kinjo, Ariga: "Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19958-72, (2013) (PubMed).

    Abe, Takahashi-Niki, Takekoshi, Shimizu, Kitaura, Maita, Iguchi-Ariga, Ariga: "Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation." in: The Journal of biological chemistry, Vol. 288, Issue 39, pp. 27764-76, (2013) (PubMed).

    Miyazawa, Tashiro, Kitaura, Maita, Suto, Iguchi-Ariga, Ariga: "Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19191-203, (2011) (PubMed).

  • Target
    PFDN6 (Prefoldin Subunit 6 (PFDN6))
    Andere Bezeichnung
    PFDN6 (PFDN6 Produkte)
    Synonyme
    hke2 antikoerper, ke-2 antikoerper, pfd6 antikoerper, h2-ke2 antikoerper, pfdn6a antikoerper, 23.m05913 antikoerper, H-2Ke2 antikoerper, Ke-2 antikoerper, Pfdn6 antikoerper, H2-KE2 antikoerper, HKE2 antikoerper, KE-2 antikoerper, PFD6 antikoerper, zgc:66282 antikoerper, pfdn6 antikoerper, pfdn6b antikoerper, Ke2 antikoerper, prefoldin subunit 6 S homeolog antikoerper, prefoldin subunit 6 (predicted) antikoerper, prefoldin subunit 6 antikoerper, prefoldin subunit 6 L homeolog antikoerper, pfdn6.S antikoerper, SPAC3A11.13 antikoerper, BBOV_IV004800 antikoerper, AOR_1_2254174 antikoerper, CMU_042830 antikoerper, pfdn6 antikoerper, Pfdn6 antikoerper, PFDN6 antikoerper, pfdn6.L antikoerper
    Hintergrund
    PFDN6 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. This protein also binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
    Molekulargewicht
    14583
    Gen-ID
    10471
    NCBI Accession
    NP_001172110, NP_001252524, NP_001252525, NP_055075
    UniProt
    O15212
    Pathways
    Unfolded Protein Response
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