RFC5 Antikörper (AA 170-200)
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- Target Alle RFC5 Antikörper anzeigen
- RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))
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Bindungsspezifität
- AA 170-200
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RFC5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogen
- This RFC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human RFC5.
- Klon
- RB17319
- Isotyp
- Ig Fraction
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- Applikationshinweise
- WB: 1:1000. WB: 1:1000. WB: 1:1000. FC: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 6 months
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- Target
- RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))
- Andere Bezeichnung
- RFC5 (RFC5 Produkte)
- Synonyme
- zgc:110313 antikoerper, 2610020K06Rik antikoerper, 2610209F07Rik antikoerper, 36.5kDa antikoerper, 36kDa antikoerper, Recc5 antikoerper, RFC36 antikoerper, replication factor C (activator 1) 5 antikoerper, replication factor C subunit 5 antikoerper, replication factor C subunit 5 L homeolog antikoerper, rfc5 antikoerper, Rfc5 antikoerper, RFC5 antikoerper, rfc5.L antikoerper
- Hintergrund
- The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. RFC5 is the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.
- Molekulargewicht
- 38497
- Gen-ID
- 5985
- NCBI Accession
- NP_001123584, NP_031396, NP_853556
- UniProt
- P40937
- Pathways
- Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA
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