ARFGAP1 Antikörper (C-Term)

Produktnummer ABIN388996

Produktdetails anti-ARFGAP1 Antikörper

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Bindungsspezifität: AA 377-406, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARFGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ARFGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-406 amino acids from the C-terminal region of human ARFGAP1.

Klon: RB4855

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:8000. WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-ARFGAP1 Antikörper (ABIN388996)

Nishimura, Uchida, Yachi, Kudlyk, Lupashin, Inoue, Taguchi, Arai: "Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs." in: Molecular biology of the cell, Vol. 24, Issue 22, pp. 3534-44, (2013) (PubMed).

Zhang, Major, Takanashi, Camp, Nishiya, Peters, Ginsberg, Jian, Randazzo, Schultz, Moon, Ding: "Small-molecule synergist of the Wnt/beta-catenin signaling pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 18, pp. 7444-8, (2007) (PubMed).

Details zu ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Andere Bezeichnung: ARFGAP1 (ARFGAP1 Produkte)

Synonyme: ARF1GAP antikoerper, HRIHFB2281 antikoerper, AI115377 antikoerper, Arf1gap antikoerper, Arf GAP1 antikoerper, arf1gap antikoerper, atfb1 antikoerper, atfb3 antikoerper, jlns1 antikoerper, k(v)7.1 antikoerper, kcna8 antikoerper, kcna9 antikoerper, kv1.9 antikoerper, kv7.1 antikoerper, kvlqt1 antikoerper, lqt antikoerper, lqt1 antikoerper, rws antikoerper, sqt2 antikoerper, wrs antikoerper, ARFGAP3 antikoerper, ADP ribosylation factor GTPase activating protein 1 antikoerper, ADP-ribosylation factor GTPase activating protein 1 antikoerper, ADP ribosylation factor GTPase activating protein 1 S homeolog antikoerper, putative ADP-ribosylation factor GTPase activating protein 1 antikoerper, ATP-dependent RNA helicase DBP9 antikoerper, ARFGAP1 antikoerper, Arfgap1 antikoerper, arfgap1.S antikoerper, Tb11.01.6060 antikoerper, arfgap1 antikoerper, LMJF_32_1230 antikoerper, MGYG_02419 antikoerper

Hintergrund: ARFGAP1 is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine.

Molekulargewicht: 44668

Gen-ID: 55738

NCBI Accession: NP_001268411, NP_001268412, NP_001268413, NP_060679, NP_783202

UniProt: Q8N6T3

Pathways: p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response