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USP15 Antikörper (N-Term)

USP15 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB4337 unconjugated
Produktnummer ABIN388904
  • Target Alle USP15 Antikörper anzeigen
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    Bindungsspezifität
    • 8
    • 7
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-180, N-Term
    Reaktivität
    • 48
    • 26
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 46
    • 1
    • 1
    Kaninchen
    Klonalität
    • 46
    • 1
    Polyklonal
    Konjugat
    • 26
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser USP15 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 28
    • 9
    • 8
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This USP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human USP15.
    Klon
    RB4337
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product USP15 Primärantikörper
  • Applikationshinweise
    IF: 1:25. WB: 1:1000. WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:2500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    USP15 (Ubiquitin Specific Peptidase 15 (USP15))
    Andere Bezeichnung
    USP15 (USP15 Produkte)
    Synonyme
    USP15 antikoerper, UNP antikoerper, UNPH-2 antikoerper, UNPH4 antikoerper, 4921514G19Rik antikoerper, AI327321 antikoerper, E430033I05Rik antikoerper, Gcap18 antikoerper, mKIAA0529 antikoerper, Ubp109 antikoerper, ubiquitin specific peptidase 15 antikoerper, universal stress protein UspA antikoerper, ubiquitin carboxyl-terminal hydrolase 15 antikoerper, USP15 antikoerper, RR_RS05795 antikoerper, LOC100090554 antikoerper, usp15 antikoerper, Usp15 antikoerper
    Hintergrund
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Molekulargewicht
    112419
    Gen-ID
    9958
    NCBI Accession
    NP_001239007, NP_001239008, NP_006304
    UniProt
    Q9Y4E8
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