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USP8 Antikörper (C-Term)

USP8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB04288 unconjugated
Produktnummer ABIN388891
  • Target Alle USP8 Antikörper anzeigen
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Bindungsspezifität
    • 10
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1058-1087, C-Term
    Reaktivität
    • 46
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 2
    • 1
    Kaninchen
    Klonalität
    • 44
    • 2
    Polyklonal
    Konjugat
    • 26
    • 4
    • 4
    • 4
    • 4
    • 4
    Dieser USP8 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 26
    • 18
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This USP8 (UBPY) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1058-1087 amino acids from the C-terminal region of human USP8 (UBPY).
    Klon
    RB04288
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product USP8 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    USP8 (Ubiquitin Specific Peptidase 8 (USP8))
    Andere Bezeichnung
    USP8 (UBPY) (USP8 Produkte)
    Synonyme
    HumORF8 antikoerper, UBPY antikoerper, AI574262 antikoerper, AW557536 antikoerper, Ubpy antikoerper, mKIAA0055 antikoerper, ubiquitin carboxyl-terminal hydrolase 8 antikoerper, ubiquitin specific peptidase 8 antikoerper, LOC9310109 antikoerper, MGYG_00369 antikoerper, USP8 antikoerper, Usp8 antikoerper
    Hintergrund
    USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation. USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1. USP8 may regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2. As revealed by structur/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1. Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.
    Molekulargewicht
    127523
    Gen-ID
    9101
    NCBI Accession
    NP_001122082, NP_001122083, NP_005145
    UniProt
    P40818
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