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USP4 Antikörper (C-Term)

USP4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4269 unconjugated
Produktnummer ABIN388883
  • Target Alle USP4 Antikörper anzeigen
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    Bindungsspezifität
    • 15
    • 14
    • 10
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 903-933, C-Term
    Reaktivität
    • 55
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 54
    • 1
    • 1
    Kaninchen
    Klonalität
    • 55
    • 1
    Polyklonal
    Konjugat
    • 24
    • 7
    • 7
    • 7
    • 5
    • 5
    • 1
    Dieser USP4 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 39
    • 36
    • 7
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This USP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 903-933 amino acids from the C-terminal region of human USP4.
    Klon
    RB4269
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product USP4 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Laurell, Velázquez-Fernández, Lindsten, Juhlin, Enberg, Geli, Höög, Kjellman, Lundeberg, Hamberger, Larsson, Nilsson, Bäckdahl: "Transcriptional profiling enables molecular classification of adrenocortical tumours." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 141-52, (2009) (PubMed).

  • Target
    USP4 (Ubiquitin Specific Peptidase 4 (USP4))
    Andere Bezeichnung
    USP4 (USP4 Produkte)
    Synonyme
    UNP antikoerper, Unph antikoerper, F730026I20Rik antikoerper, Unp antikoerper, mKIAA4155 antikoerper, ubiquitin specific peptidase 4 antikoerper, ubiquitin specific peptidase 4 (proto-oncogene) antikoerper, USP4 antikoerper, Usp4 antikoerper
    Hintergrund
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
    Molekulargewicht
    108565
    Gen-ID
    7375
    NCBI Accession
    NP_001238806, NP_003354, NP_955475
    UniProt
    Q13107
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